Does the mic and audio performance change when switching between 3.5mm and USB-A/C connector?

Microphone and audio quality will be converted to analog when you use Zone Wired Earbud with a 3.5mm connector. You can enjoy digital audio quality with USB-C and A connector. This is because the 3.5mm connector has an analog audio signal. 

It would happen as the 3.5mm connector has an analog audio signal while USB-C and A are in digital. When you use Zone Wired Earbuds with the 3.5m connector, microphone and audio quality will be converted to analog.